According to EWN, the musician, who had a brain tumour, died around midday afterÂ being taken to hospital in the morning.
The star brought us many hit tracks including Nkalakatha, Godoba, Tornado and Sgelekeqe. Fans last saw Mandoza on stage performing at theÂ 'Thank You SABC' concert which took place last weekend.
Several people, including fans, celebrities and politicians, have taken to social media to send their tributes.
Eish RIP Mandoza— Dj Dimplez (@DjDimplez) September 18, 2016
We mourn the death of Mandoza together, the dispossessed, historically disadvantaged, privileged, those who are captured, the rich and poor!— ChuckNorris' Advisor (@Ari_Gold99) September 18, 2016
I am deeply saddened to learn about the passing of well known musician, Mandoza. This is a huge loss to our country. HSRIP
â€” Herman Mashaba (@HermanMashaba) September 18, 2016
It really saddens me that he is gone. Especially after a long fight for survival. Thank you for all the seeds u planted Bhut' Mandoza
â€” MarazA (@Marazamc) September 18, 2016
Damn man!!! Mandoza left us??? Argh no man!!! This life thing is sooo short. #RIP to the legend!!!
â€” FillUpOrlandoStadium (@CassperNyovest) September 18, 2016
RIP to Mandoza - a life cut short but well lived.
â€” RSA Min of Sport (@MbalulaFikile) September 18, 2016
Mandoza will go down as the only South African artist who almost erased racism and painted a rainbow nation with Nkhalakhatha #RIP Legend
â€” The Instigator (@AmBlujay) September 18, 2016
At least once a day for the past 10 years I'm asked "Hey DK.. Where is Mandoza?". Today I'm heartbroken to know that I won't be asked that question ever again. My friend and SA music legend is gone. He was a true game changer that we all loved. It didn't matter if you were from Soweto, Sandton or Somerset West - Mandoza made you get down. There will never be another quite like him. I'll miss you dawg, thank you for the music and the memories we had together. Deepest condolences to Mpho and the family #Mandoza ?
May his soul rest in peace.